Towards New Standards Symposium 2019
P. Bulens, MD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium

Philippe Bulens completed his medical studies at the KU Leuven in 2013, summa cum laude. Since 2013, Philippe has been working as a resident radiation oncology at the University Hospitals Leuven. In 2015, he was granted a four-year aspirant research mandate by the Research Foundation Flanders (FWO) for the PhD project
“Treatment Individualisation for Patients with Rectal Cancer: Towards an Organ Preserving Approach”. In this project, which is currently in its final status, clinical cancer research is performed with a translational focus on predictive markers and tumour metabolism. In 2019, Philippe won the PhD Prize awarded by the Belgian Society for Radiation Oncology (BeSTRO) for his research. As of August 2019, he will start his final year of clinical training as a radiation oncologist.
A. D'Hoore, MD, PhD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium

D’Hoore André graduated as MD at the Catholic University of Leuven, Belgium in 1988. He became surgeon in 1994 and joined the staff of Abdominal Surgery at the University Clinic Leuven. He received an international postgraduate training in colorectal surgery at the Cleveland Clinic in Fort Lauderdale, St. Mark’s Hospital in London and the Hôpital Cantonal in Geneva.
In 2000 he became a European Board Qualified Surgeon in ColoProctology. In 2007 he obtained his PhD and is full professor at the Faculty of Medicine, Catholic University of Leuven and contributes to graduate an postgraduate teaching of students and trainees in abdominal surgery.
He is the actual chair of the department of abdominal surgery at the University Hospitals Leuven and is the president of the Collegium Chirurgicum Belgicum.
Recently he received the honorary membership of the American and Mexican Society of Colorectal Surgery.
André D’Hoore is a regular invited speaker at international surgical meetings. His scientific work resulted in more than 200 peer-reviewed papers.
He is a founding member of the European Section of Coloproctology (ESCP) and is the founder of the surgical branch of the European Crohn’s and Colitis Organisation (S-ECCO).

J. Dekervel, MD, PhD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium

Jeroen Dekervel was born in Menen on December 18th, 1984. He obtained his medical degree at the KU Leuven in 2009, magna cum laude. From 2009 until 2017, he was a resident internal medicine and later gastroenterology at UZ Leuven and in affiliated hospitals (Sint-Andriesziekenhuis Tielt, AZ Groeninge Kortrijk). Between 2012 and 2016, he left the clinic to do translational cancer research, mainly in the field of acquired drug resistance to systemic therapies, resulting in a degree Doctor of Biomedical Sciences. Since May 2018, he is member of the Digestive Oncology team at the University Hospitals Leuven. His current research focuses on diagnostic and predictive genomic biomarkers for digestive tumors.
E. Dresen, MD, PhD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium

Elleke Dresen serves as an abdominal radiologist at the University Hospitals Leuven since 2014. Dr. Dresen has earned her Ph.D. at the Faculty of Health, Medicine and Life Sciences in Maastricht, the Netherlands in 2009. Her dissertation was addressed to the multidisciplinary approach to locally advanced and recurrent rectal cancer. She is an active member of the oncological multidisciplinary team meetings, especially concerning colorectal and gynaelogical cancer patients. She practises all aspects of abdominal radiology, including MRI, CT, PET/CT, ultrasound, fluoroscopy and nonvascular abdominal interventions. Her current research is mainly concentrated at whole-body diffusion-weighted magnetic resonance imaging in patients with colorectal and ovarian cancer with the aim of optimizing treatment planning.
T. Maughan, MD (University of Oxford, United Kingdom)
University of Oxford

Tim studied medicine at Cambridge and UCH, London and undertook his research training at Cambridge under Prof Norman Bleehen at the MRC Clinical Oncology and Radiotherapeutics Unit. Thereafter he worked as an NHS consultant Clinical Oncologist in Cardiff, becoming Professor of Cancer Studies in 2007. During that time, he established the first clinical research network, the Wales Cancer Trials Network, and was subsequently involved in the development of the clinical research networks across the UK. Tim’s research has focused on colorectal cancer: he leads the FOCUS4 trial of molecular selection of treatment and the MRC/CR-UK stratified medicine consortium in colorectal cancer (S:CORT). Professor Maughan was appointed Professor of Clinical Oncology and Clinical Director of the MRC-CRUK Oxford Institute of Radiation Oncology, Department of Oncology at the University of Oxford in 2011.
R. Oliva Perez, MD, PhD (Angelita & Joaquim Gama Institute, Brazil)
Angelita & Joaquim Gama Institute, Sao Paulo

Dr. Perez has graduated from the University of São Paulo School of Medicine where he has completed his surgical training under the supervision of Prof. Angelita Habr-Gama. In 2002 he was a Visiting Research Fellow at USC where he collaborated with Dr. Robert Beart. He obtained his PhD in São Paulo in 2006 in studying potential molecular targets for gene therapy in rectal cancer. After joining the Angelita & Joaquim Gama Institute and the Ludwig Institute for Cancer Research in 2004, Dr. Perez has concentrated his clinical and research activity on the management of rectal cancer, with particular interest in the prediction of response to neoadjuvant chemoradiation regimens and in the alternative organ-preserving strategies used for patients developing complete clinical response. From 2010 to 2014, Dr. Perez was a Post Doctoral fellow at the University of São Paulo in the use of molecular imaging (PET/CT) for the assessment of response of rectal tumors to chemoradiation. In 2014, Dr. Perez was awarded the Young Research Fund in São Paulo (FAPESP) to study molecular mechanisms associated with resistance/sentivity of rectal cancers to chemoradiation. Currently, he serves at the editorial board of multiple scientific surgical and oncology journals and has contributed with numerous publications to the field.
Y. Panis, MD, PhD (Hôpital Beaujon, France)
Hôpital Beaujon, France

Born in 1961, november 9th, I am Professor of Digestive Surgery since 1997 and Head of the Department of colorectal surgery in Beaujon Hospital (University Paris 7) since 2007. In clinics, my topics (for both clinical practice and publications) are focused on colorectal surgery, with special interest in IBD, rectal cancer and laparoscopy. At the end of February 2019, I have 369 citations in PubMed, with an H index of 68. In clinical research, I have organise as principal investigator, 8 multicentric randomized studies (5 already published) on early stoma closure, bowel preparation in rectal cancer surery, on bladder drainage in rectal cancer surgery, fast track program in laparoscopic colorectal cancer surgery, in one-trocart colonic surgery, and in prostethic mesh after temporary stoma closure after laparoscopic TME. Among my published papers, I have published a paper on ileal pouch anal anastomosis in Lancet journal in 1996, two papers on Annals of Surgery on segmental reversal of the small bowel for the treatment of short bowel syndrome, and one in Annals of Surgery suggesting the very low risk of infertility after laparoscopic IPAA. As chariman of the board of S-ECCO, I have participate to the recent guidelines on surgical treatment of ulcerative colitis, and as a member of EAES to the recent guidelines on early rectal cancer. I was up to the end of 2016 president of the GRECCAR Group (French group on rectal cancer treatment) and of the GETAID Surgery (French group on IBD surgery).
L. Petruzziello, MD (Fondazione Policlinico Universitario A. Gemelli, Italy)
Fondazione Policlinico Universitario A. Gemelli
Dr. Lucio Petruzziello MD is part of the team of Surgical Digestive Endoscopy of A. Gemelli Hospital in Rome (Director Prof. Guido Costamagna) and is responsible for Surgical Digestive Endoscopy at Columbus Hospital. He is also Professor of Digestive Endoscopy in the Medicine and Surgery Degree of the Catholic University of Rome and in the postgraduate degrees in Gastroenterology and General Surgery of the same University.
Dr. Petruzziello trained in Digestive Surgery and Digestive Endoscopy at the University of Rome "La Sapienza" and then spent periods of training in New York (Prof. JD Waye, Mt. Sinai Hospital), London (Prof. CB Williams, St. Marks Hospital) and Tokyo (Prof. Y Saito, National Cancer Center). His field of interest is the technique and teaching of colonoscopy and the endoscopic treatment of neoplastic lesions of the digestive tract. He is co-author of several publications in international peer-reviewed journals related to Digestive Endoscopy (Citation Index 3075, H Index 25, i10-index 34), co-author of the regional protocol for the screening of colorectal cancer in Lazio and has been reviewer for Digestive and Liver Disease and Endoscopy journals.
Dr. Petruzziello is part of the scientific committee of the European Endoscopy Training Centre (EETC) of the Catholic University in Rome where he has held, supervised and taught many diagnostic and interventional Endoscopy Courses. He is faculty member of the annual Live Demonstration Workshop on GI Endoscopy “Endolive Roma”. He is member of the Italian Society of Digestive Endoscopy (SIED) and former president of the Lazio chapter of this Society. He is also member of the European Society for Gastrointestinal Endoscopy (ESGE) and of the GISCoR (Italian Group for Colorectal Cancer Screening). He has given numerous lectures and has been visiting Professor at national and international congresses and post-graduate courses in Italy and abroad. He has also been Coordinator of the National and Regional Courses for Self-Assessment and Re-training in Colonoscopy within the National Program of Colorectal Cancer Screening held by the Ministry of Health.
Since 2010 he is Lecturer and Tutor in Colonoscopy Technique at the Summer School of Gastroenterology of the United European Gastroenterology (UEG).

H. Piessevaux, MD, PhD (Cliniques universitaires Saint-Luc, UCLouvain, Belgium)
Cliniques universitaires Saint-Luc, UCLouvain, Belgium

Hubert Piessevaux is Professor of Medicine at UCLouvain and Head of the Department of Hepato-gastroenterology at Cliniques universitaires St-Luc, Brussels Belgium. Professor Piessevaux, born in 1966, earned a medical degree Magna Cum Laude from UCLouvain in 1990, specialized in gastroenterology both at UCLouvain and KULeuven in 1996 before starting a full-time staff position at Cliniques universitaires Saint-Luc. Hubert started research in functional GI disorders leading to the successful defence of a PhD thesis entitled ‘Pathophysiological role of fundic tension receptors in functional dyspepsia' with Professor Jan Tack from KULeuven as promoter. He subsequently developed research interest in the development of techniques for the resection of superficial tumours of the gastro-intestinal tract. From 2004 on, he was one of the pioneers of colorectal endoscopic submucosal dissection in Europe. He trained numerous colleagues in this technique in collaboration with Japanese experts. Hubert also developed expertise in statistical analysis of oncology trials. Hubert Piessevaux has been active in several Belgian and European scientific organisations, serving a.o. as secretary-general of the Société Royale Belge de Gastroentérologie and as secretary of the Belgian Society of Gastro-Intestinal Endoscopy.
P. Quirke, BM, PhD, FRCPath (University of Leeds, United Kingdom)
BM, PhD, FRCPath
University of Leeds

Professor Phil Quirke BM, PhD, FRCPath, FMedSci, FRCSEd (ad hominem), FFPath-RCPI (Hon)
Is the Yorkshire Cancer Research Centenary Professor of Pathology in the School of Medicine at the University of Leeds, UK and honorary Consultant Pathologist, Leeds Teaching Hospitals NHS Trust.Phil attended Medical School at Southampton University and postgraduate training and PhD at Leeds University.
He leads the section of pathology and tumour biology in the University of Leeds and has a major research interest in Bowel cancer, molecular and digital pathology and postgraduate academic education. Honorary Fellow/ honorary member of six international surgical societies and Fellow of the Academy of Medical Sciences, UK.
Phil’s major achievements have been:
i) To identify the cause of local recurrence in rectal cancer and open up the way to minimise this occurrence.
ii) To show that simple observations of anatomy and cancer surgery and the specimens that are removed by surgeons can identify the quality of the operating surgeon and that educational interventions using excellent surgeons can improve outcomes in a number of countries. With Gina Brown contributed to evaluation of the value of MRI imaging in rectal cancer.
iii) Pathology, molecular ad digital pathology contributions to the QUASAR, CLASICC, CR07, ROLARR, FOCUS1-4, FOXTROT, TREC and many other clinical trials.
iv) Leads the Pathology of the English Bowel Cancer Screening programme since 2006 and coordinated the Pathology chapter of the European guidelines on bowel cancer screening.
Newer areas of work:
v) Identifying variations in clinical practice and the use of big data to understand multidisciplinary team clinical results and improve outcomes with Professor Eva Morris.
vi) Exploration of the impact of the microbiome on the causation, screening and treatment of colorectal cancer.

E. Rullier, PhD (Haut-Lévèque Hospital Bordeaux, France)
Haut-Lévèque Hospital Bordeaux

Eric Rullier is born in 1961 and was educated at the University of Bordeaux, where he was graduated General Surgeon in 1991 and Professor of Surgery in 2001. He was Chief of the Colorectal Unit at Saint-Andre Bordeaux University Hospitals in 1995, then Head of the Department of Surgery in 2011, and is Chairman of Colorectal Surgery at Magellan Centre, Haut-Levèque Bordeaux University Hospitals since 2016. Eric Rullier developed clinical research in rectal cancer. His main topics are low rectal cancer, sphincter and organ preservation, and mini invasive surgery. He demonstrated the oncologic safety of the technique of intersphincteric resection and participated to the European development of laparoscopic surgery in rectal cancer. He also proposed a classification of low rectal cancer to standardize surgery and facilitate sphincter preservation.
Eric Rullier founded in 2005 the GRECCAR (Groupe de REcherche Chirurgical du CAncer Rectal) to develop innovative research on rectal cancer at a national level. He also cofounded PELVICARE at Bordeaux Foundation University in 2015, to develop the Bordeaux’ Colorectal School and is Director of European courses and Masterclasses for TME and colorectal surgery. He is past President of the GRECCAR, active member of the ESCP and Fellow of the ASCRS. His scientific production includes more than 100 publications and 400 international conferences on rectal cancer.
X. Sagaert, MD, PhD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium

Xavier Sagaert is a Professor at the Faculty of Medicine of the University of Leuven, a staff member at the Department of Pathology, University Hospitals Leuven and Director of the residency program of anatomic pathology at the University Hospitals Leuven, Leuven, Belgium. He completed his medical studies from the University of Leuven in 2000 before undertaking residencies in internal medicine and anatomic pathology between 2000 and 2009 along with gaining a PhD in Medical Sciences in 2007.
His main clinical focus is on gastrointestinal tract and hematopathology. His research interests include gastrointestinal cancer (pathogenesis, genetics), confocal laser endomicroscopy, immunopathology and non-Hodgkin lymphomas. He has authored or co-authored over 35 articles in peer-reviewed publications as well as a book chapter. He is a member of various editorial boards including the World Journal of Gastrointestinal Oncology, and World Journal of Gastrointestinal Pathology. He is also a member of the American Society of Clinical Oncology and an associate faculty member of the Faculty of 1000 Medicine.

A. Spinelli, MD, PhD (Humanitas Research Hospital, Italy)
Humanitas University

Prof. Antonino Spinelli MD PhD is leading the Unit of Colon and Rectal Surgery and is Associate Professor of Surgery at the Humanitas University.
He trained for two years (2003-2005) at the University of Berlin – Charitè, at the Dept of General, Visceral and Transplantation Surgery and gained his PhD on Enhanced Recovery Protocols in Colorectal Surgery in 2011.
He is dedicated to the development of innovative techniques in minimally invasive colorectal surgery, included single-port surgery and robotic surgery, and is one of the pioneers of the modern transanal approach for rectal surgery.
He is Member of the Executive Board of the Italian Society of Colorectal Surgery and Chairman of its Guidelines Committee.
Prof. Spinelli serves as Associate Editor for Colorectal Disease, the leading European Journal in the field of colorectal surgery, as Editorial Board Member for the Journal of Crohn’s Colitis and for Coloproctology, and as Associate Editor of Diseases of the Colon and Rectum (official journal of the American Society of Colon and Rectal Surgeons).
Prof. Spinelli is regularly invited speaker to many prestigious International Meetings (as, among others UEGW, ECCO, European Colorectal Congress, ESCP) and has scientific collaborations with many prestigious institutions worldwide for colorectal Surgery. He has been invited to give more than 190 talks/lectures, among others at the Karolinska Institutet in Stockholm, Mount Sinai Hospital in Toronto, UZ in Leuven, John Radcliffe Hospital in Oxford, St. Mark’s Hospital in London. Prof. Spinelli is currently serving as Member of the Scientific Programme Committee of the European Society of Coloproctology and Chair of Scientific Programme Committee of the International Colorectal Forum / Alpine Colorectal Meeting.
He authored/co-authored 110 Pubmed indexed papers, with an IF > 430 and an H Index of 32 (Google Scholar).
Prof. Spinelli was awarded with the Honorary Fellowship of the Czech Society of Surgery in 2016 and with the Honorary Membership of the Brazilian College of Digestive Surgeons (CBCD) in 2017. In May 2018, Prof Spinelli was appointed Honorary Clinical senior Lecturer at University College London.
S. Tejpar, MD, PhD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium

Molecular Oncology at the Center for Human Genetics, KULeuven, I became in 09-2003 an Associate Professor in the Dept of Gastro Enterology, Digestive Oncology Unit, UZ Leuven. I work as a part time clinician, part time researcher (Senior Clinical Investigator of the Fund for Scientific Research- Flanders (Belgium)) , with a focus on basic and translational research in colorectal cancer. I am a Board member of the EORTC and lead the Translational Research Division at the EORTC.
E. Van Cutsem, MD, PhD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium

Eric Van Cutsem, MD, PhD, is since 2000 full professor at the University of Leuven. He is head of the division of Digestive Oncology at the University Hospitals Gasthuisberg Leuven (UZ Leuven) and University of Leuven (KUL) and is board member of the Leuven Cancer Institute (LKI). He is member of the Belgian Royal Academy of Medicine since 2015 and became Doctor Honoris Causa at the University of Warschau. He is president of the Belgian Foundation Against Cancer since October 2016.
Professor Van Cutsem obtained his medical degree in 1983 from the University of Leuven, specialized in internal medicine and gastroenterology and he was awarded his PhD in 1994. He has a mandate as clinical researcher of the Fund for Scientific Research (FWO) since 2003. Throughout his training he has spent several months in England, Switzerland, the USA and the Netherlands and he has been involved in clinical and research projects in digestive oncology. Eric Van Cutsem is a member of several scientific organizations. He is/was a member of the Scientific Program Committee and/or educational committee of ASCO, ASCO-GI cancers symposium, ESMO, UEG and ECCO. He served for ESMO as executive board member 2011-2013 and is since 2014 on the ESMO press committee. He was secretary from 2000 to 2003 and chair of the EORTC-GI group from 2003 to 2007 and is chairman of PETACC (Pan-European Trials on Adjuvant Colon Cancer) since 2008; he was board member of the EORTC 2009-2015 and president of European Society of Digestive Oncology (ESDO) and is co-chairman of the European Neuro-Endocrine Tumour Society (ENETS) registry.
He was chairman of the governmental colon cancer prevention task force in Flanders, Belgium and was president of BGDO (Belgian Group Digestive Oncology) 2010-2016 and is past-president since 2016. He was president of FAPA (Familial Adenomatous Polyposis Association) till 2016 and is now vice-president and is member of the general assembly of Kom tegen Kanker (Flemish Cancer Ligue). He is medical director of Europacolon (patient advocacy group).
He has been the founder (1999) of and is chair of the Scientific Committee of the ESMO GI/ World Congress on Gastrointestinal Cancer in Barcelona (in partnership with ESMO since 2005), the largest meeting on GI cancer with ± 3500 participants
A. Wolthuis, MD, PhD (University Hospitals Leuven, Belgium)
University Hospitals Leuven, Belgium
Albert Wolthuis graduated medical school in 2002 (KU Leuven, cum laude). He was a surgical resident for 6 years to become general surgeon in 2008. He further trained in abdominal surgery with specialization in colorectal surgery. Since 2011 he is a staff member at the department of Abdominal Surgery (UZ Leuven) with special interest in minimally invasive surgery, transanal approaches, redo surgery, debulking and HIPEC. After his PhD in 2015 he became assistant professor at the KU Leuven.