Session 1: Evolution and Epidemiology
Ansgar Schulz, Friedrich Loeffler Institute, Germany
Whole genome sequencing of various bunyaviruses and other arboviruses using MinION nanopore technology
Igor Starinskij, MRC-University of Glasgow Centre for Virus Research, United Kingdom
Research tools for Erve virus, a neglected European nairovirus
Jorlan Fernandes, Universidade do Estado do Rio de Janeiro and Fundação Oswaldo Cruz, Brazil
Old reservoirs, New Virus – The diversity of Mammarenavirus in Brazil.
Pritesh Lalwani, Instituto Leônidas e Maria Deane and Fundação Oswaldo Cruz, Brazil
Oropouche Virus Resurgence: Investigating the Role of a Novel Reassortant in Brazil
Nazif Elaldi, Sivas Cumhuriyet University, Turkey
Crimean-Congo Haemorrhagic Fever Virus Diversity, Clinical Severity, Blood Virus Titres and Outcomes, Turkey, 2020–2021
Jorlan Fernandes, Universidade do Estado do Rio de Janeiro and Fundação Oswaldo Cruz, Brazil
Reptarenavirus (Arenaviridae: Bunyavirales) in captive snake (Boa constrictor) from Brazil
Session 2: Virus Entry and Assembly
Gaya Amarasinghe, Washington University School of Medicine, USA
Role of LDL related receptor proteins in bunyaviral infection
Solene Denolly, Centre International de Recherche en Infectiologie, France
The low-density lipoprotein receptor and apolipoprotein E associated with CCHFV particles mediate CCHFV entry into cells
Aseel Alyahyawi, University of Leeds, United Kindgom
Investigating the entry mechanisms of a new member of the Orthobunyavirus genus
Lennart Sänger, Bernhard Nocht Institute for Tropical Medicine. Germany
An RNA to Rule Them All: Critical Steps in Lassa Virus Ribonucleoparticle Assembly and Recruitment
Juan Oswaldo Concha Casaverde, University of Sao Paulo, Brazil
The host factors Rab27a and Myosin Va are required for efficient cell egress of Oropouche virus
François-Loïc Cosset, Centre International de Recherche en Infectiologie, France
The PACS-2 protein and trafficking motifs in CCHFV Gn and Gc cytoplasmic tails govern CCHFV assembly
Nicole Tischler, Fundación Ciencia & Vida – University of San Sebastián, Chile
Molecular insights into the hantavirus Gn/Gc spikes during viral cell:cell transmission, cell entry and their biogenesis
Samantha Hover, University of Leeds, United Kingdom
Utilising cryo-ET to investigate the orthobunyavirus spike organisation and the mechanisms of the K+ requirement for virus entry
Session 3: Virus Replication
Catherine Beauchemin, Interdisciplinary Theoretical and Mathematical Sciences Program, RIKEN, Japan
A framework to individually measure virus replication steps and identify experimental artifacts
Kate Gilroy, University of Leeds, United Kingdom
Developing a Molecular Toolkit for the Live Cell Investigation of Arenavirus Replication
Alejandro Brun, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, CSIC, Spain Novel replication-competent Rift Valley fever viruses expressing fluorescent or bioluminescent reporter genes
Harry Williams, Bernhard Nocht Institute for Tropical Medicine, Germany
Structural snapshots of phenuivirus cap-snatching and transcription
Jeremy Keown, University of Warwick, United Kingdom
Structural characterisation of the CCHFV polymerase
Eurico De Arruda Neto, University of São Paulo, Brazil
The tropical phlebovirus Candiru replicates in human cell lines and causes apoptosis of HuH-7 liver cells by both intrinsic and extrinsic pathways
Yeonjae Lee, University of Leeds, United Kingdom
Investigating the structure and function of bunyavirus ribonucleoproteins
Piotr Gerlach, IMOL - Polish Academy of Sciences, Poland
Preliminary insight into La Crosse orthobunyavirus transcription termination mechanism
Dani Vaughan, University of Nottingham, United Kingdom
TRIM25 and ZAP mediated antiviral inhibition of arenavirus replication
Selina Krueger, Bernhard Nocht Institute for Tropical Medicine, Germany
Potential interactions between Bunyavirus L proteins and host proteins of the DDX family
Richard Kormelink, Wageningen University & Research, Netherlands
Structural insights into the TSWV RNA polymerase, the largest plant virus replication machinery
Kirsten Bronsvoort, Wageningen University & Research, Netherlands
Mimicking the ovine placental barrier to study arbovirus infection in vitro
Sophia Qais, University of Leeds, United Kingdom
Developing a Split GFP System to Illuminate Nairovirus Trafficking and Replication
Janna Scherf, Bernhard Nocht Institute for Tropical Medicine, Germany
Limited high-throughput screening compatibility of the phenuivirus cap-binding domain
Nicholas Smith, University of Leeds, United Kingdom
Visualising the arenavirus RNA synthesis machinery in action
Rebecca Panteli, University of Cambridge, United Kingdom
Discovering host factors required for the replication and spread of Oropouche virus
Eliana Dukhno, IMOL - Polish Academy of Sciences, Poland
Impact of the La Crosse orthobunyavirus S segment mRNA 3′ UTR on translation
Paul Wichgers Schreur, Wageningen Bioveterinary Research and BunyaVax,Netherlands
Single-cell transcriptomic profiling of ovine liver cells upon Rift Valley fever virus infection
Alex Childs, University of Nottingham, United Kingdom
Utilising cryo-orbiSIMS to investigate the structure-function relationships of arenavirus intergenomic regions
Owen Byford, University of Leeds, United Kingdom
LCMV arenavirus requires single residue S343 phosphorylation
Hayley Pearson, University of Leeds, United Kingdom
Using Bunyamwera virus as a tool to explore a new paradigm for endocytic potassium channel function in cells.
Moh Egy Rahman Firdaus, IMOL - Polish Academy of Sciences, Poland
La Crosse orthobunyavirus nucleoprotein interacts with the stress granule factor G3BP1
Session 4: Antiviral Immunity and pathogenesis
Clayton Winkler, National Institute of Allergy and Infectious Diseases, NIH, USA
CCR2 and CCR7 synergistically control inflammatory monocyte recruitment during La Crosse virus encephalitis but monocyte immunological function in the brain is impaired
Younho Choi, Cleveland Clinic Florida Research and Innovation Center, USA
The NSs of SFTSV inhibits the human antiviral RNAi pathway through its interaction with Ago2
José Luiz Proenca Modena, University of Campinas, Brazil
B-cell response against Oropouche virus
Stephen Graham, University of Cambridge, United Kingdom
A protein-based molecular toolkit to study, detect, prevent and treat Oropouche fever
Deepashri Rao, National Institute of Allergy and Infectious Diseases, NIH, USA
Signaling through TNFR1 is required for survival in Crimean-Congo hemorrhagic fever virus infection
Benjamin Nilsson-Payant, TWINCORE Centre for Experimental and Clinical Infection Research, Germany
Molecular basis of hantavirus defective viral genomes in innate immune regulation
Moshe Dessau, Bar Ilan University, Israel
Structural investigation of RNA silencing suppressors from an Emaravirus
Abraham Ayanwale, Hannover Medical University, Germany
Molecular basis of arenavirus defective viral genomes in the host antiviral response
Barry Rockx, Wageningen University & Research, Netherlands
A pan-orthohantavirus preclinical human lung xenograft mouse model
Andrew Clarke, MRC-University of Glasgow Centre for Virus Research, United Kingdom
Examination of Bhanja virus isolates using reverse genetic approaches reveals disparate interferon antagonism phenotypes
Jordan Clark, Icahn School of Medicine at Mount Sinai, USA Cross-binding antibodies capable of neutralizing diverse hantaviruses are produced in response to Puumala virus infection
James Dunlop, MRC-University of Glasgow Centre for Virus Research, United Kingdom
Super-resolution 3D-SIM microscopy of Rift Valley fever virus NSs nuclear filaments labelled with an unnatural amino-acid fluorophore reveals an intricate matrix of fine microfilaments
Jasmine Batyrbayeva Brown, The Pirbright Institute, United Kingdom
Decoding differential activity of native and recombinant type I interferons against Rift Valley fever virus infection
Session 5: Vector Biology
Esther Schnettler, Bernhard Nocht Institute for Tropical Medicine, Germany
Dicer 2 mutations in Aedes aegypti cells lead to a diminished antiviral function against RVFV and BUNV infection
Samantha Clark, Louisiana State University, USA
The good, the BATV, and the ugly: first evaluation of BATV vector competence in Louisiana mosquitoes
Marine Petit, University of Surrey, United Kingdom
Temporal multi-omics analysis of Severe Fever with Thrombocytopenia syndrome virus (SFTSV) infection in tick cells reveal novel antiviral effectors.
Patrick Höller, Bernhard Nocht Institute for Tropical Medicine. Germany
Unveiling Tahyna Virus Transmission: Vector Competence of Mosquitoes from Europe
Eurico De Arruda Neto, University of São Paulo, Brazil
Vertical transmission of Oropouche virus in C57BL/6 mice and infection of murine and human trophoblasts
Session 6:
David Hawman, National Institute of Allergy and Infectious Diseases, NIH, United Kingdom
Antibodies against the CCHFV nucleoprotein require the intracellular Fc-receptor TRIM21 for protection.
Belen Borrego, Center for Animal Health Research, National Center for Agricultural and Food Research and Technology, CSIC, Spain
Dynamics of the potential attenuating mutations of the RVF vaccine candidate 40Fp8 in the absence of (efficient) immune responses
Paul Wichgers Schreur, Wageningen Bioveterinary Research and BunyaVax, Netherlands
Safety and immunogenicity of the live-attenuated hRVFV-4s Rift Valley fever vaccine in healthy adults
Darryl Falzarano, Vaccine and Infectious Disease Organization, Canada
Differential Glycosylation Profiles of Lassa Virus GPC in Expi293 and ExpiCHO Suspension Cultures – Implications for Subunit Vaccine Production
Virginia Aida-Ficken, Centers for Disease Control and Prevention and Auburn University College of Veterinary Medicine, USA
Inhibiting the Lassa Virus Polymerase with a Novel Macrocyclic Compound
Peter Hart, Coalition for Epidemic Preparedness Innovations, United Kingdom
The Coalition for Epidemic Preparedness Innovations (CEPI): A Global coalition to develop vaccines for epidemics and pandemics.
Benjamin Gutjahr, Friedrich Loeffler Institute, Germany
High immunogenicity of CCHFV vaccine candidates in ruminants
Alejandro Brun, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, CSIC, Spain
Safety and efficacy of 40Fp8 vaccine candidate against Rift Valley fever in pregnant sheep
Dominik Vogel, Bernhard Nocht Institute for Tropical Medicine, Germany
Assay development for high-throughput antiviral compound screening against bunyavirus L protein
Catalina Florez, USAMRIID, USA
Therapeutic efficacy of SNV-specific monoclonal antibodies in a novel STAT2 knockout Syrian Golden hamster disease model for Sin Nombre Virus infection
Emma Bentley, Medicines and Healthcare products Regulatory Agency, United Kingdom
Use of bunyavirus pseudotyped virus-based neutralisation assays to support serological reference materials development
Jack Saunders, University of Oxford, United Kindgdom
Adenoviral-vectored CCHFV vaccines confer protection against lethal challenge in mice via Gc or GP38-specific immunity ,